Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
Home Print this page Email this page
Users Online: 1008

Year : 2008  |  Volume : 5  |  Issue : 2  |  Page : 43-47

Evaluation of lipid profile in hypothyroid patients-our experience

1 Department of Biochemistry, Govind Ballabh Pant Hospital, New Delhi, India
2 Department of Biochemistry, Maulana Azad Medical College and associated hospitals, New Delhi, India

Correspondence Address:
D Tayal
Department of Biochemistry, Govind Ballabh Pant Hospital, New Delhi
Login to access the Email id

Source of Support: None, Conflict of Interest: None

Rights and PermissionsRights and Permissions

Thyroid hormones regulate the activity of some key enzymes in lipoprotein transport. In the present study, lipid profile of patients with sub clinical hypothyroidism and overt hypothyroidism who presented at G.B.Pant Hospital, New Delhi, India was reviewed for a period of one year. Serum TSH, T4 and T3 were assayed using ELISA based kits. The concentration of serum total cholesterol, HDL- cholesterol and triglycerides were measured on Auto analyzer by standard methods. Data collected was subjected to standard statistical analysis. The patients of hypothyroidism had significantly higher levels of serum cholesterol as compared to the euthyroid controls (p < 0.05). The HDL levels were comparatively lower in the hypothyroid patients. It can be concluded that hypothyroidism is associated with dyslipidemia i.e. increased Total cholesterol and LDL- cholesterol levels and decreased HDL-cholesterol levels. Lipid disorders are probably responsible for the development of atherosclerosis in hypothyroid patients in Indian population.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded376    
    Comments [Add]    

Recommend this journal