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Year : 2010  |  Volume : 7  |  Issue : 3  |  Page : 91-92

Graves' disease presenting as osteomalacia and proximal myopathy - An uncommon presentation of a common disorder

Department of Medicine, Government Medical College, Srinagar, Kashmir-190012, India

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M H Bhat
Department of Medicine, Government Medical College, Srinagar, Kashmir-190012
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Source of Support: None, Conflict of Interest: None

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We present a case of a 30 year old Kashmiri female with sudden onset bilateral lower extremity weakness who was found to have hyperthyroidism and severe os­teomalacia on further evaluation. Serum calcium, phosphorous, 24 hour urine cal­cium excretion and serum Vitamin D levels were low and alkaline phosphatase level was high. A diagnosis of hyperthyroidism with osteomalacia and myopathy was made. This demonstrates a rare case of osteomalacia and proximal myopathy as the initial presentation of Graves' disease and drastic improvement on treatment with anti-thyroid drugs and Vitamin D supplementation.

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