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Year : 2011  |  Volume : 8  |  Issue : 2  |  Page : 17-21

Can we differentiate Graves' disease from thyroiditis on clinical and biochemical ground?

Department of Diabetes & Endocrinology, Manipal Hospital, 98, Rustom Bagh, Bangalore, India

Correspondence Address:
A Bhattacharyya
Department of Diabetes & Endocrinology, Manipal Hospital, 98, Rustom Bagh, Bangalore
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Source of Support: None, Conflict of Interest: None

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Graves' disease and thyroiditis are two common causes of hyperthyroidism in our clinical practice. Isotope scan is the test for differentiating Graves' disease from thyroiditis with thyrotoxicosis but not available widely in India [Figure 1]. In our cohort of consecutive 228 cases of Graves' disease and thyroiditis, we tried to compare the clinical and biochemical features at diagnosis. Our data favours a diagnosis of Graves' disease with positive family history, high Crooks Wayne's index, high free T4 and low ESR at the time of diagnosis. But these alone may not be sufficient as differentiating pointer between Graves' disease and thyroiditis with thyrotoxicosis.

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