Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
Home Print this page Email this page
Users Online: 929

Year : 2012  |  Volume : 9  |  Issue : 3  |  Page : 88-92

Effects of submaximal aerobic exercise on thyroid hormones in hypoxic conditions in trained young men

1 Department of Exercise Physiology, Islamic Azad University, Central Tehran Branch, Tehran, Iran
2 Department of Clinical, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran
3 Department of Biostatistics, National Public Health Management Center and Department of Statistics and Epidemiology, Tabriz University of Medical Sciences, Tabriz, Iran

Correspondence Address:
Suzan Sanavi
Akhavan Center, Monyrieh squ, Valiye-Asr Ave, 1113813111
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0973-0354.99651

Rights and Permissions

Background: There are many conflicting opinions regarding the effects of hypoxia on thyroid hormones in different situations. This study evaluates the effect of exercise-induced hypoxia on thyroid hormones and thyroid-stimulating hormone (TSH) in trained young men. Materials and Methods: The participants consisted of 17 healthy men, aged 20-24 years, with mean maximal oxygen uptake and body mass index of 48.6 ± 3.96 ml/kg/min and 21.6 ± 0.91 kg/m 2 , respectively. They did 30-min running on treadmill, at the intensity of 70% of maximal heart rate, in normoxia and three different levels of simulated hypoxic conditions at 2750, 3250, and 3750 m heights. The sessions were interspaced with 72-hour resting breaks. Blood samples for hormonal assays were obtained before exercise and at 0 h and 1 h after exercise. Results: Data analysis, using mixed models, showed no statistically significant hormonal difference among the hypoxic conditions (P > 0.05) except increased thyroxin levels following exercise in all sessions , which were significant only in normoxia and 2750 m height (P < 0.05), without any significant changes in serum triiodotyronine and TSH. Conclusion: With respect to different reports surrounding the effects of high-altitude-induced hypoxia on pituitary-thyroid axis (including stimulatory, inhibitory, or changeless effects), this study revealed only significant increased thyroxin level at 1200 (normoxia) and 2750 m heights, following exercise. These contradictory findings may be attributed to the degree of prescribed hypoxia, planning of natural or simulated height, activity level and type, and study duration. However, for a precise conclusion, further research is recommended.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded498    
    Comments [Add]    
    Cited by others 1    

Recommend this journal