Thyroid Research and Practice

ORIGINAL ARTICLE
Year
: 2021  |  Volume : 18  |  Issue : 1  |  Page : 1--5

Primary hypothyroidism on follow-up in a cohort of Indian patients with subacute thyroiditis


Pramila Kalra1, KM Prasanna Kumar2 
1 Professor and Consultant, Department of Endocrinology, M S Ramaiah Medical College and Hospitals, Bengaluru, Karnataka, India
2 Ex HOD and Professor Department of Endocrinology, M S Ramaiah Medical College and CEO CDEC Bengaluru, Karnataka, India

Correspondence Address:
Dr. Pramila Kalra
Ramaiah Medical College, Bengaluru, Karnataka
India

Objectives: Subacute thyroiditis (SAT) is a temporary dysfunction of the thyroid gland and is commonly due to its viral infection. Permanent hypothyroidism after recovery from SAT has been reported in various studies. Methodology: This was a prospective study conducted in two tertiary care centers in South India to follow-up these cases for the development of permanent primary hypothyroidism at 1-year follow-up after recovery from SAT. Results: The total number of cases followed up was 146, including 103 females (70.5%) and 43 males (29.5%). Females' mean age was 33.03 ± 11.7 years, and males' mean age was 40.17 ± 11.84 years. Seven patients reported the second attack of thyroiditis. The mean thyroid-stimulating hormone (TSH) recorded at baseline was 0.042 ± 0.056 µIU/ml. Permanent hypothyroidism was seen in 19.86% of the cases at a 1-year follow-up and was found to be higher in patients with lower TSH at baseline. The females and males were affected at a younger age as compared to other studies. The incidence of permanent hypothyroidism was found to be higher as compared to some but lesser compared to a few others. The iodine supplementation could also be one of the postulates for this higher incidence of hypothyroidism. The severity of thyrotoxicosis was a significant determinant of the future development of hypothyroidism. Conclusions: The patients with SAT need to be followed up for the development of permanent hypothyroidism. The prevalence of hypothyroidism at 1 year was 19.86% after an attack of thyroiditis.


How to cite this article:
Kalra P, Prasanna Kumar K M. Primary hypothyroidism on follow-up in a cohort of Indian patients with subacute thyroiditis.Thyroid Res Pract 2021;18:1-5


How to cite this URL:
Kalra P, Prasanna Kumar K M. Primary hypothyroidism on follow-up in a cohort of Indian patients with subacute thyroiditis. Thyroid Res Pract [serial online] 2021 [cited 2021 Dec 9 ];18:1-5
Available from: https://www.thetrp.net/article.asp?issn=0973-0354;year=2021;volume=18;issue=1;spage=1;epage=5;aulast=Kalra;type=0