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Figure 1: Distribution of serum thyroid-stimulating hormone values within the normal percentile intervals (2.5th–97.5th) in a mild iodine-deficient population of 340 healthy rural young Indian women who completed the follow-up longitudinal study after exclusion criteria.Note approximately 98% population lies within upper limit thyroid-stimulating hormone cut-offs i.e., 3.7, 4.8 and 5.74 mIU/L in 1st, 2nd, 3rd trimester respectively. Any women falling beyond these cut offs (2%–4% of population) would require treatment. Whereas according to the cut-offs in practice in India (following International guidelines) a much higher segment of population would be potential candidates for treatment, and thus stand the risk of misclassification |
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